On this special episode of Pathways from the New York State Trauma-Informed Network and Resource Center, Dr. Elizabeth Meeker welcomes Dr. Nadine Burke Harris for a rich discussion on Adverse Childhood Experiences (ACEs) and their profound impact on long-term health outcomes. As a medical doctor (pediatrician and first Surgeon General of California), Dr. Burke Harris shares her journey of understanding how childhood trauma affects biological development.
Key topics of this episode include:
- Expanding our understanding of adversity beyond the original 10 ACE categories
- The groundbreaking ACEs study, published in 1998, and its findings about childhood adversity
- How toxic stress affects – and changes – brain, immune, and hormonal systems
- The relationship between childhood experiences and lifelong health risks like stroke and heart disease
- Methods for regulating and treating the toxic stress response


